5 Sprays that Kill Dust Mites in 2021

Dust mites are found almost everywhere and can be pesky for people that have a low tolerance for allergies. If you have a dust mite problem, it is important to find the perfect solution for reducing these allergens. Since dust mites are so small, they can hide anywhere and most homes have millions and millions of these allergens. Although you may not be able to completely rid your home of dust mites, figuring out a way to get rid of as many as you can is important!

There are two common types of dust mite sprays:

1. Sprays that eliminate and kill dust mites

2. Anti-Allergen sprays that reduce dust mite allergies

We have separated the best dust mite sprays into these two categories. 

Dust Mite Killing Sprays

Great for Spot Treating

Ortho Home Dust Mite Aerosol Spray

Great for Infestations

Premo Dust Mite Killer Spray

Dust Mite Allergy Sprays

Great Versatility

Allergy & Asthma Clean Allergen Spray

Great Scent

Febreze Fabric Refresher Allergen Reducer Spray

Also Great

Allsearch ADMS Anti-Allergen Spray

Dust Mite Killing Sprays & Reviews

If you are looking for a spray that can help to kill dust mites, it is important that you make sure that you know where you are spraying and who lives in your home. If you have pets or small children, make sure that you are using a product that is safe.

Ortho Home Defense Dual-Action Dust Mite Aerosol Spray
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The Ortho Home Defense Dial-Action Dust Mite killer is an easy-to-use spray that kills bed bugs and dust mites, and also stops them from producing eggs. Only 10 inches tall, 3.63 inches wide, and 1.4 pounds, it’s the perfect size sprayer for killing mites in hard-to-reach places. 

The product is safe to use on beds, furniture, and luggage. Additionally, this anti-mites spray formula is extremely fast acting and gets the job done. This spray is also a very effective solution to bed bugs. The spray will kill mites and their eggs, minimizing future issues.


  • Can be used for spot treating
  • Lasts up to 2 weeks when sprayed on the carpet
  • Can be used for any surfaces
  • Kills hard to see bugs and insects
  • Is made of fast acting materials so that it can kill on contact
  • Can last for days after spraying


  • Spray can is small and does not last long
  • Not for a permanent fix

Ortho Home Defense Customer Reviews:

According to Walmart.com, this product has a 4.1 out of 5-star rating, with over 60% of the customers feeling like this product worked great and for a long period of time. Many felt that this product was a good choice because it can be used on all surfaces. One reviewer raved, “I ordered 2 bottles of this and it definitely works. It butchered the bugs on contact!”

Other customers felt that the price was fair, and they recommend this product for both their homes, offices and where they travel to help keep allergens down.

Trial Results

We tested this spray over the course of two weeks. Here were the results: 

  • It killed mites and bed bugs on contact
  • Was effective for 11 days
  • It was safe to use on furniture
Premo Dust Mite Killer Spray
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The Premo bed bug, lice, and mite killer is one of the most popular dust mite killers on the market. Made from natural ingredients, this product is proven to kill bugs and is safe to use in your home. 

This spray is effective for small and medium infestations and will remain effective for up to two weeks. Scent free, this will take care of bed bugs, dust mites, bird mites, fleas, lice, and many other types of crawling insects. 

The Premo Mite Killer Spray is easy to use and formulate to be sprayed on a variety of different materials, such as bedding, furniture, clothing, and carpets. 


  • Natural ingredients, safe to use around children and pets
  • Kills dust mites, spider mites, mold mites, stink bugs, cockroaches, silverfish, fleas and ants
  • Does not stain furniture
  • Scent-free and leaves no residue behind
  • Lasts up to 2 weeks after first use


  • Does not last longer than 2 weeks.

Premo Mite Killer Spray Customer Reviews

According to Walmart.com, this product has over 175 reviews with a 4.1 out of 5-star rating. Most of the customers felt that this product worked very well with over 75% giving it a 4 or more-star review.

Trial Results

This spray came in an easy-to-use bottle and was scent-free. It left behind no residue and we were able to spray it on multiple types of surfaces around our home. Within a few days, we saw no more ants or silverfish in our apartment, so we consider this a major success! 

Dust Mite Allergy Sprays & Reviews

For those that suffer from allergies, there are sprays formulated to provide some relief. With these sprays, customers are able to eliminate some of the pesky allergy symptoms that they have when dealing with dust mites.

Great Versatility:
Allergy Asthma Clean Anti-Allergen Spray

Allergy & Asthma Clean Allergen Spray
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This spray is perfect for those who are trying to fight against the allergens caused by dust mites. It arrives in a concentrated form and you simply fill the bottle to the top with tap water and start spraying. The best part of this spray is how versatile it is, as it can be used on any surface without any issues.

Depending on what’s giving you allergies, you will use this product differently during the week. For dust mite allergies, it is recommended to spray both the air and surfaces 3 times per week. You will mist every room in your house as well as soft surfaces like the sofa, bedding, pillows, curtains, and carpet.

What happens when you spray is that the mixture is atomized and attracts as well as attaches to allergen molecules and proteins. This extra weight brings them down, encapsulates them, and neutralizes them.  


  • Can be used on many types of surfaces
  • Safe for pets, plants, and people
  • Does not stain


  • More expensive than other options
  • Reduces allergies but does not fully eliminate them

Allergy Asthma Clean Spray Customer Reviews:

According to Walmart.com, this has a 4.3 out of 5-stars with 3,400 views. With more than 80% of the customers giving it a 4 or more-star review, they are saying that this product helped to get rid of allergies such as stuffy noses, sneezy, itchy eyes, and sinus infections.

Trial Results

My neighbor is very allergic to our cat and when an allergy attack comes on he can sneeze more than 30 times in a row! To prevent this, I keep the cat out of certain areas of the home if he is coming by, but he still has occasional reactions. However, using this spray I found it is very effective at controlling and inactivating the cat dander. As a result, my neighbor has not had an allergic reaction for the past 3 weeks. He feels more comfortable coming by now and I have not noticed a smell when using this and it has not stained any furniture or clothing.

Great Scent:
Febreze Fabric Refresher Allergen Reducer-Spray

Febreze Fabric Refresher Allergen Reducer Spray
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If you are looking for a nice scent to go along with your allergy relieving spray, then the  Febreze Fabric Refresher Allergen Reducer-Spray will be right up your alley. 

This product will minimize up to 95% of inanimate allergens from pollen, pet dander, and dust mite matter. It will also eliminate any tough odors that are trapped in fabrics and come in a variety of different sets. 

The great thing about this product is not only doing it get rid of allergens; it also helps to get rid of odors in your home all while keeping your fabrics fresh and smelling great.

To use, spray in a sweeping motion over fabrics and let dry before sitting. Because allergens become trapped in fabrics throughout your home, everyday use will send them flying into the air, causing irritation. 


  • There are many different scents to choose from
  • Safe for most fabrics
  • Helps get rid of allergens found in carpets, bedding, curtains, and other fabrics


  • Scents can be strong for some time
  • Not for use on leather, suede, or silk – can damage these materials

Febreze Fabric Refresher Allergen Reducer-Spray Customer Reviews:

According to Walmart.com, the Febreze Fabric Refresher Allergen Reducer-Spray has a 4 out of the 5-star review. This product has 30 reviews with over 67% of the customers giving the product a 4 or higher star review.

Most of the customers that reviewed this product felt that this product was a great choice for getting rid of unwanted allergens. 

Other customers talked about how well the product smelled and that it helped to keep the home smelling well and helped to keep the furniture fresh and clean feeling.

Trial Results

We were heading out of town and a friend volunteered to come by and take care of our cat while we were gone, despite having a mild cat allergy. We sprayed our apartment with the Febreze Allergen reduced spray right before we left and when we returned 4 days later, she told us that she didn’t have a single allergy symptom. The place also smelled great when we returned! 

Allsearch ADMS Anti-Allergen Spray
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The Allersearch ADMS Anti-Allergen Spray is perfect for those that are trying to fight against a wide variety of allergens. This spray helps with dust mites, pollen, mold, mildew, and even pet dander.

Coming in a 32-ounce spray bottle, it is recommended to retract surfaces every 90 days, so this product has a longer active life than the others on our list. 

The Allersearch Anti-Allergen Spray does not have tannic acid or benzyl benzoate which allows customers to use this product on furniture of all colors without staining or hurting the fabric.


  • Safe for pets, plants, and people
  • Can be used on any type of furniture or curtains
  • Does not stain
  • Kills mildew and mold instantly
  • Works for 30 days


  • Has a strong smell in some cases
  • Odor does not smell great

Allersearch ADMS Anti-allergen Spray Customer Reviews:

According to Amazon.com, the Allersearch ADMS Anti-Allergen Spray has a 4.5 out of 5-star review with 2,300 views. This allergy reducer spay has more than 80% of the customers giving it a 4 or more-star review with customers saying that this product helped to get rid of allergies such as stuffy noses and sinus infections.

Other customers talked about how this product helped to get rid of their allergies and was safe to use around their children and animals. One customer even talked about how they were able to keep kittens even though their son was allergic, after using this product

Trial Results

We used the Allersearch ADMS spray around our home and in our basement right before leaving for a weekend trip and not only did it eliminate our allergy symptoms when we returned, it also removed the musky odor in our basement. This must be because unlike the others on our list, this spray also attacks mold spores. It does have a strong smell at first but it dissipated after a day. Because we were out it didn’t affect us, but I am not sure how I would feel about regularly spraying it while we are home. 


Dust mites can cause allergies such as runny or stuffy noses, red and itchy eyes, itchy skin, coughing, sneezing, and other upper respiratory problems. Those that have strong allergy reactions can find themselves having flu-like symptoms when dealing with dust mites.

When dust mites cause allergies, it is important to find a way to reduce or eliminate the allergens that are caused by these dust mites to help keep you and your home healthy. In order to find the perfect dust mite deterrent, it is important to research the products and find the perfect product for your home, office, and even your vehicle.

Are you also interested in a dehumidifier for your laundry room? We will tell you the best dehumidifier for laundry rooms 

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